I spent a career in research and I can tell you that mice are excellent models for discovery, AMA

Why does my left bollock look like jackfruit suddenly?

According to Freud, because your mum had a face like a jackfruit and you’re secretly lusting for her.

mice are excellent models for discovery

Not really. What’s the translate rate to humans? 9%?

Mice can model some diseases well, but they are not universally good models.

Not universal, for example we use zebrafish for spine defect models since mouse spine has an odd curve/hunch that doesn’t line up as well. But for general metabolism/pathology/embryonic development they do a great job of mimicking human disease under the microscope. Its not always 1:1 but we learn a lot from these little guys.

Do you volunteer to have a stroke induced so researchers then can test their treatment?

they come to clinic every hour in a big city.

Nurse: “Sir, would you like to try this new and experimental treatment, or do you prefer proven methods?” Stroke victim: “Hhhrrrngn!” Nurse: “I’m sorry, what was that?” Stroke victim: "Hhhhhhhrhghn!!! Hrhh … " *dies*

Great idea, Sherlock!

Yes, this research would move so much faster if we simply induced strokes in people and injected them with stuff to see what happens… /s

I think tpihkal just volunteered

I always thought that the /s was a stupid thing, but judging from the down votes on your comment, I guess it’s a necessity

I have seen many people hold this opinion unironically.

They have a point. Mouse model research translation to human disease has a poor track record. Mouse model labs spin in circles between models and never try to translate into humans. Some diseases stall for decades in models.

The mouse’s brain plasticity is orders of magnitude higher than a human’s.