I run Truenas scale on home server and on the off-site backup at a friend’s house. ZFS Snapshots get synced to backup server nightly. The snapshot system is nice because it only needs to send what has changed since the last synced snapshot.

Now that I have it setup it is mostly no effort on my part. But the initial ramp up to understand Truenas and ZFS was a second job for a few weeks. HexOS may be good choice if you want the power of Truenas but the handholding of setup wizards and such. But HexOS is currently $200 and Truenas is free. Pay in time or dollars.