Do you want to run TensorFlow Lite / LiteRT models? PyTorch Mobile? TensorRT? onnx? YOLO? vLLM? Something else? The recommendations will vary based on your use case.
Google Coral was decent for TensorFlow Lite, but it’s EOL (end of life) now. I’ve got the dual TPU Mini PCIe version in my home server, via a PCIe adapter board. I use it for object detection with Blue Iris + CodeProject AI and it works pretty well for that use case.
Hailo-8 is supposed to be like a more powerful version of the Coral, but I don’t have experience with it. It supports a bunch of frameworks: TensorFlow, TensorFlow Lite, Keras, PyTorch and ONNX. I’d be interested in hearing other people’s thoughts on it.
I don’t know if any of these work over USB though. They’re usually internal devices. Google marketed the Coral USB as being for development and testing only, pointing people to the M.2 and PCIe versions for production usage.
As for something totally different… There’s the Nvidia Jetson single board computer which supports TensorRT, but I don’t have experience with it either. I also think it’s a bit older too. You could also consider getting a newer mini PC with a AMD Ryzen AI processor in it, or an Nvidia DGX Spark.
Google’s latest TPUs are only available in their cloud - they’re not selling the hardware to end users any more.